I am surprise when I don't see a need to use null in f#. It use a generic record type "option", which is a very elegant solution to express nullness. In c#, we have reference type and value type, in .net 1/1.1, we express nullness for reference type using "null", in .net 2 above, we can use Nullable type of value type. However, f# unify this using option.
The null keyword is a valid keyword in the F# language, and you have to use it when you are working with .NET Framework APIs or other APIs that are written in another .NET language. The two situations in which you might need a null value are when you call a .NET API and pass a null value as an argument, and when you interpret the return value or an output parameter from a .NET method call. For more please refer to MSDN